U-Blot® RBP1 Polyclonal Antibody

Name: U-Blot® RBP1 Polyclonal Antibody
SKU: WP3310
Availability: InStock

$268.00

Size:50μL

SKU: WP3310-50

Catalog No.: WP3310

Specification: 50μL/100μL

Stock: In stock

U-Blot® RBP1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010],

Product Overview

Catalog No.: WP3310
SKU: WP3310-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RBP1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 72kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: RBP1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: RALBP1 RLIP1 RLIP76
Protein Name: RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1)
Other Name: --
Organism-1: Human
Gene ID-1: 10928
SwissProt-1: Q15311
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q62172
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q62796
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Peripheral membrane protein . Cytoplasm, cytosol . Cytoplasm, cytoskeleton, spindle pole . Nucleus . Mitochondrion . Cytosolic protein that transiently associates with the mitotic spindle poles in early prophase, and dissociates from them after completion of mitosis (By similarity). Targeted to the plasma membrane through its interaction with RALB, directed by FGF signaling. Docking on the membrane is required to transduce the Ral signal (By similarity). Recruited by RALA to the mitochondrion during mitosis where it regulates mitochondrial fission (PubMed:21822277). Nuclear localization is cell cycle dependent while membrane localization is seen in adherent cells (PubMed:22319010). The region involved in membrane association could form transmembrane domains and expose a part of the protein extracellularly (Probable). .