U-Blot® MKKS rabbit pAb

Name: U-Blot® MKKS rabbit pAb
SKU: WP3591
Availability: InStock

$268.00

Size:50μL

SKU: WP3591-50

Catalog No.: WP3591

Specification: 50μL/100μL

Stock: In stock

U-Blot® MKKS rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],

Product Overview

Catalog No.: WP3591
SKU: WP3591-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MKKS
Reactivity: Human,Mouse
Application: WB
MW(Calculated): --
MW(Observed): 65kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human MKKS AA range: 166-216
Sequence: --
Specificity: This antibody detects endogenous levels of MKKS at Human/Mouse
Gene Name: MKKS BBS6
Protein Name: MKKS
Other Name: McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin;Bardet-Biedl syndrome 6 protein;
Organism-1: Human
Gene ID-1: 8195
SwissProt-1: Q9NPJ1
Organism-2: Mouse
Gene ID-2: 59030
SwissProt-2: Q9JI70
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol . Nucleus . The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome.