U-Blot® DGCR8 rabbit pAb

Name: U-Blot® DGCR8 rabbit pAb
SKU: WP3755
Availability: InStock

$268.00

Size:50μL

SKU: WP3755-50

Catalog No.: WP3755

Specification: 50μL/100μL

Stock: In stock

U-Blot® DGCR8 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

Product Overview

Catalog No.: WP3755
SKU: WP3755-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: DGCR8
Reactivity: Human,Mouse
Application: WB
MW(Calculated): --
MW(Observed): 85kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human DGCR8 AA range: 467-517
Sequence: --
Specificity: This antibody detects endogenous levels of DGCR8 at Human/Mouse
Gene Name: DGCR8 C22orf12 DGCRK6 LP4941
Protein Name: DGCR8
Other Name: Microprocessor complex subunit DGCR8;DiGeorge syndrome critical region 8;
Organism-1: Human
Gene ID-1: 54487
SwissProt-1: Q8WYQ5
Organism-2: Mouse
Gene ID-2: 94223
SwissProt-2: Q9EQM6
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Nucleus, nucleolus . Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron-dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies (PubMed:17159994).