U-Blot® POLK rabbit pAb

Name: U-Blot® POLK rabbit pAb
SKU: WP3792
Availability: InStock

$268.00

Size:50μL

SKU: WP3792-50

Catalog No.: WP3792

Specification: 50μL/100μL

Stock: In stock

U-Blot® POLK rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016],

Product Overview

Catalog No.: WP3792
SKU: WP3792-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: POLK
Reactivity: Human,Mouse
Application: WB
MW(Calculated): 96kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human POLK AA range: 272-322
Sequence: --
Specificity: This antibody detects endogenous levels of POLK at Human/Mouse
Gene Name: POLK DINB1
Protein Name: POLK
Other Name: --
Organism-1: Human
Gene ID-1: 51426
SwissProt-1: Q9UBT6
Organism-2: Mouse
Gene ID-2: 27015
SwissProt-2: Q9QUG2
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Detected throughout the nucleus and at replication foci (PubMed:12414988). Recruited to DNA damage sites in response to ultraviolet irradiation: N6-methyladenosine (m6A)-containing mRNAs accumulate in the vicinity of DNA damage sites and their presence is required to recruit POLK (PubMed:28297716). .