U-Blot® CASQ1 rabbit pAb

Name: U-Blot® CASQ1 rabbit pAb
SKU: WP4033
Availability: InStock

$268.00

Size:50μL

SKU: WP4033-50

Catalog No.: WP4033

Specification: 50μL/100μL

Stock: In stock

U-Blot® CASQ1 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes the skeletal muscle specific member of the calsequestrin protein family. Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells. This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle. This protein is absent in patients with Duchenne and Becker types of muscular dystrophy. [provided by RefSeq, Jun 2013],

Product Overview

Catalog No.: WP4033
SKU: WP4033-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CASQ1
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 44kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human CASQ1 AA range: 322-372
Sequence: --
Specificity: This antibody detects endogenous levels of CASQ1 at Human/Mouse/Rat
Gene Name: CASQ1 CASQ
Protein Name: CASQ1
Other Name: --
Organism-1: Human
Gene ID-1: 844
SwissProt-1: P31415
Organism-2: Mouse
Gene ID-2: 12372
SwissProt-2: O09165
Organism-3: Rat
Gene ID-3: 686019
SwissProt-3: P19633
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Endoplasmic reticulum . Sarcoplasmic reticulum . Sarcoplasmic reticulum lumen . Sarcoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side . Mitochondrion matrix . This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Preferentially forms linear and round aggregates in the endoplasmic reticulum (ER) of resting cells (PubMed:28895244). In a minority of cells, homogeneously detected in the ER lumen (PubMed:28895244). Colocalizes with STIM1 at endoplasmic reticulum in response to a depletion of intracellular calcium (PubMed:27185316). .