U-Blot® FLNC rabbit pAb

Name: U-Blot® FLNC rabbit pAb
SKU: WP4198
Availability: InStock

$268.00

Size:50μL

SKU: WP4198-50

Catalog No.: WP4198

Specification: 50μL/100μL

Stock: In stock

U-Blot® FLNC rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP4198
SKU: WP4198-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: FLNC
Reactivity: Human,Mouse
Application: IHC,IF
MW(Calculated): 300kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-200;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human FLNC AA range: 335-385
Sequence: --
Specificity: This antibody detects endogenous levels of FLNC at Human/Mouse
Gene Name: FLNC ABPL FLN2
Protein Name: FLNC
Other Name: --
Organism-1: Human
Gene ID-1: 2318
SwissProt-1: Q14315
Organism-2: Mouse
Gene ID-2: 68794
SwissProt-2: Q8VHX6
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . A small amount localizes at membranes. In striated muscle cells, it predominantly localizes in myofibrillar Z lines, while a minor fraction localizes with subsarcolemme. Targeting to developing and mature Z lines is mediated by the intradomain insert.