U-Blot® DESP rabbit pAb

Name: U-Blot® DESP rabbit pAb
SKU: WP4464
Availability: InStock

$268.00

Size:50μL

SKU: WP4464-50

Catalog No.: WP4464

Specification: 50μL/100μL

Stock: In stock

U-Blot® DESP rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],

Product Overview

Catalog No.: WP4464
SKU: WP4464-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Desmoplakin
Reactivity: Human,Mouse
Application: IHC,IF
MW(Calculated): 316kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-200;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human DESP AA range: 1546-1596
Sequence: --
Specificity: This antibody detects endogenous levels of DESP at Human/Mouse
Gene Name: DSP
Protein Name: Desmoplakin
Other Name: Desmoplakin;DP;250/210 kDa paraneoplastic pemphigus antigen;
Organism-1: Human
Gene ID-1: 1832
SwissProt-1: P15924
Organism-2: Mouse
Gene ID-2: 109620
SwissProt-2: E9Q557
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell junction, desmosome . Cytoplasm, cytoskeleton . Cell membrane . Innermost portion of the desmosomal plaque. Colocalizes with epidermal KRT5-KRT14 and simple KRT8-KRT18 keratins and VIM intermediate filaments network (PubMed:12802069). Localizes at the intercalated disk in cardiomyocytes (By similarity). .