- Target
- MACF1
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 813kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human MACF1 AA range: 5623-5673
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of human MACF1
- Gene Name
- MACF1 ABP620 ACF7 KIAA0465 KIAA1251
- Protein Name
- Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 23499
- SwissProt-1
- Q9UPN3
- Organism-2
- Mouse
- Gene ID-2
- 11426
- SwissProt-2
- Q9QXZ0
- Organism-3
- Rat
- Gene ID-3
- 11426
- SwissProt-3
- D3ZHV2
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- [Isoform 2]: Cytoplasm, cytoskeleton . Cytoplasm . Golgi apparatus . Cell membrane . Cell projection, ruffle membrane . The phosphorylated form is found in the cytoplasm while the non-phosphorylated form associates with the microtubules (By similarity). Localizes to the tips of microtubules (PubMed:27693509). Associated with the minus-end of microtubules via interaction with CAMSAP3 (PubMed:27693509). APC controls its localization to the cell membrane which is critical for its function in microtubule stabilization (PubMed:20937854). .; [Isoform 1]: Cytoplasm . Golgi apparatus . Localizes to the tips of microtubules. .