- Target
- REST
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 121kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human REST AA range: 593-643
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of human REST
- Gene Name
- REST NRSF XBR
- Protein Name
- RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 5978
- SwissProt-1
- Q13127
- Organism-2
- Mouse
- Gene ID-2
- 19712
- SwissProt-2
- Q8VIG1
- Organism-3
- Rat
- Gene ID-3
- 19712
- SwissProt-3
- O54963
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Cytoplasm . Colocalizes with ZFP90 in the nucleus (By similarity). In response to hypoxia, there is a more pronounced increase in levels in the nucleus as compared to the cytoplasm (PubMed:27531581). In aging neurons, increased levels in the nucleus as compared to the cytoplasm (PubMed:24670762, PubMed:30684677). .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Nucleus .; [Isoform 4]: Cytoplasm .