- Target
- PDCD6
- Reactivity
- Human,Mouse
- Application
- WB
- MW(Calculated)
- 21kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human PDCD6 AA range: 98-148
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of human PDCD6
- Gene Name
- PDCD6 ALG2
- Protein Name
- Programmed cell death protein 6 (Apoptosis-linked gene 2 protein) (Probable calcium-binding protein ALG-2)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 10016
- SwissProt-1
- O75340
- Organism-2
- Mouse
- Gene ID-2
- 18570
- SwissProt-2
- P12815
- Organism-3
- --
- Gene ID-3
- 18570
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Endoplasmic reticulum membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane . Cytoplasm . Nucleus . Endosome . Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus (PubMed:17045351). Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules (PubMed:21122810). In response to calcium increase, relocates from cytoplasm to COPII vesicle coat (PubMed:27716508). Localizes to endoplasmic reticulum exit site (ERES) (PubMed:27813252). .