U-Blot® MYO1C rabbit pAb

Name: U-Blot® MYO1C rabbit pAb
SKU: WP5298
Availability: InStock

$268.00

Size:50μL

SKU: WP5298-50

Catalog No.: WP5298

Specification: 50μL/100μL

Stock: In stock

U-Blot® MYO1C rabbit pAb Learn more

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U-Blot® MYO1C rabbit pAb

Product Overview

Catalog No.: WP5298
SKU: WP5298-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MYO1C
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 117kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human MYO1C AA range: 700-750
Sequence: --
Specificity: This antibody detects endogenous levels of human MYO1C
Gene Name: MYO1C
Protein Name: Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Other Name: --
Organism-1: Human
Gene ID-1: 4641
SwissProt-1: O00159
Organism-2: Mouse
Gene ID-2: 17913
SwissProt-2: Q9WTI7
Organism-3: Rat
Gene ID-3: 17913
SwissProt-3: Q63355
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Cytoplasm . Nucleus . Colocalizes with RNA polymerase II. Absent from nucleoli and does not colocalize with RNA polymerase I. Translocates to nuclear speckles upon exposure to inhibitors of RNA polymerase II transcription.; [Isoform 2]: Cytoplasm. Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, stereocilium membrane . Cell projection, ruffle . Cytoplasmic vesicle . Colocalizes with CABP1 and CIB1 at cell margin, membrane ruffles and punctate regions on the cell membrane. Colocalizes in adipocytes with GLUT4 at actin-based membranes. Colocalizes with GLUT4 at insulin-induced ruffles at the cell membrane. Localizes transiently at cell membrane to region known to be enriched in PIP2. Activation of phospholipase C results in its redistribution to the cytoplasm (By similarity). .; [Isoform 3]: Nucleus, nucleoplasm. Nucleus, nucleolus. Nucleus, nuclear pore complex. Colocalizes with RNA polymerase II in the nucleus. Colocalizes with RNA polymerase I in nucleoli (By similarity). In the nucleolus, is localized predominantly in dense fibrillar component (DFC) and in granular component (GC). Accumulates strongly in DFC and GC during activation of transcription. Colocalizes with transcription sites. Colocalizes in the granular cortex at the periphery of the nucleolus with RPS6. Colocalizes in nucleoplasm with RPS6 and actin that are in contact with RNP particles. Colocalizes with RPS6 at the nuclear pore level. .