- Target
- SETD8
- Reactivity
- Human,Mouse
- Application
- WB
- MW(Calculated)
- 43kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human SETD8 AA range: 282-332
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of human SETD8
- Gene Name
- SETD8 KMT5A PRSET7 SET07 SET8
- Protein Name
- N-lysine methyltransferase SETD8 (H4-K20-HMTase SETD8) (Histone-lysine N-methyltransferase SETD8) (Lysine N-methyltransferase 5A) (PR/SET domain-containing protein 07) (PR-Set7) (PR/SET07) (SET domain-containing protein 8)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 387893
- SwissProt-1
- Q9NQR1
- Organism-2
- Mouse
- Gene ID-2
- 67956
- SwissProt-2
- Q2YDW7
- Organism-3
- --
- Gene ID-3
- 67956
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus. Chromosome. Specifically localizes to mitotic chromosomes. Colocalized with SIRT2 at mitotic foci. Associates with chromosomes during mitosis; association is increased in a H(2)O(2)-induced oxidative stress-dependent manner. Associates with silent chromatin on euchromatic arms. Not associated with constitutive heterochromatin.