- Target
- MEFV
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 86kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human MEFV AA range: 517-567
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of human MEFV
- Gene Name
- MEFV MEF
- Protein Name
- Pyrin (Marenostrin)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 4210
- SwissProt-1
- O15553
- Organism-2
- Mouse
- Gene ID-2
- 54483
- SwissProt-2
- Q9JJ26
- Organism-3
- Rat
- Gene ID-3
- 54483
- SwissProt-3
- Q9JJ25
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- [Isoform 1]: Cytoplasm, cytoskeleton . Cell projection, ruffle . Cell projection, lamellipodium . Nucleus . Cytoplasm . Cytoplasmic vesicle, autophagosome . Associated with microtubules and with the filamentous actin of perinuclear filaments and peripheral lamellar ruffles (PubMed:11468188). In pre-apoptotic cells, colocalizes with PYCARD/ASC in large specks (inflammasomes) (PubMed:11468188). In migrating monocytes, strongly polarized at the leading edge of the cell where it colocalizes with polymerizing actin and PYCARD/ASC (PubMed:11468188). .; [Isoform 2]: Nucleus .