U-Blot® TLR1 Polyclonal Antibody

Name: U-Blot® TLR1 Polyclonal Antibody
SKU: WP5803
Availability: InStock

$268.00

Size:50μL

SKU: WP5803-50

Catalog No.: WP5803

Specification: 50μL/100μL

Stock: In stock

U-Blot® TLR1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP5803
SKU: WP5803-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: TLR1
Reactivity: Human,Mouse,Rat
Application: IHC,IF
MW(Calculated): --
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:200-500;IF 1:50-200
Form: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Polyclonal
Clone No.: --
Immunogen: Recombinant Protein of TLR1
Sequence: --
Specificity: The antibody detects endogenous TLR1 protein.
Gene Name: TLR1
Protein Name: Toll-like receptor 1
Other Name: TLR1;KIAA0012;Toll-like receptor 1;Toll/interleukin-1 receptor-like protein;TIL;CD281
Organism-1: Human
Gene ID-1: 7096
SwissProt-1: Q15399
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9EPQ1
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, phagosome membrane ; Single-pass type I membrane protein . Membrane raft . Golgi apparatus . Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to triacylated lipoproteins, TLR2:TLR1 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. .