U-Blot® NBR1 Rabbit Polyclonal Antibody

Name: U-Blot® NBR1 Rabbit Polyclonal Antibody
SKU: WP5819
Availability: InStock

$268.00

Size:50μL

SKU: WP5819-50

Catalog No.: WP5819

Specification: 50μL/100μL

Stock: In stock

U-Blot® NBR1 Rabbit Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Product Overview

Catalog No.: WP5819
SKU: WP5819-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: NBR1
Reactivity: Human,Mouse,Rat
Application: IHC,IF
MW(Calculated): --
MW(Observed): 120kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-300;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Recombinant Protein of NBR1
Sequence: --
Specificity: The antibody detects endogenous NBR1 protein
Gene Name: NBR1 1A13B KIAA0049 M17S2 MIG19
Protein Name: Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Other Name: Next to BRCA1 gene 1 protein;Cell migration-inducing gene 19 protein;Membrane component chromosome 17 surface marker 2;Neighbor of BRCA1 gene 1 protein;Protein 1A1-3B;
Organism-1: Human
Gene ID-1: 4077
SwissProt-1: Q14596
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P97432
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q501R9
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cytoplasmic vesicle, autophagosome . Lysosome . Cytoplasm, myofibril, sarcomere, M line . In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation (PubMed:19250911). .