U-Blot® Kv10.1 Polyclonal Antibody

Name: U-Blot® Kv10.1 Polyclonal Antibody
SKU: WP5837
Availability: InStock

$268.00

Size:50μL

SKU: WP5837-50

Catalog No.: WP5837

Specification: 50μL/100μL

Stock: In stock

U-Blot® Kv10.1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP5837
SKU: WP5837-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Kv10.1
Reactivity: Human,Rat,Mouse
Application: IHC,IF
MW(Calculated): --
MW(Observed): 50kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-200;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthetic Peptide of Kv10.1 AA range: 335-385
Sequence: --
Specificity: Kv10.1 protein(A259) detects endogenous levels of Kv10.1
Gene Name: KCNG3
Protein Name: Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv10.1) (Voltage-gated potassium channel subunit Kv6.3)
Other Name: KCNG3;Potassium voltage-gated channel subfamily G member 3;Voltage-gated potassium channel subunit Kv10.1;Voltage-gated potassium channel subunit Kv6.3
Organism-1: Human
Gene ID-1: 170850
SwissProt-1: Q8TAE7
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P59053
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q8R523
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Cytoplasm . Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane (PubMed:12060745). Colocalizes with KCNB1 at the plasma membrane (PubMed:12060745, PubMed:19074135). Remains intracellular in the absence of KCNB1 (PubMed:12060745). .