U-Blot® ERK1 Rabbit Polyclonal Antibody

Name: U-Blot® ERK1 Rabbit Polyclonal Antibody
SKU: WP5874
Availability: InStock

$268.00

Size:50μL

SKU: WP5874-50

Catalog No.: WP5874

Specification: 50μL/100μL

Stock: In stock

U-Blot® ERK1 Rabbit Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP5874
SKU: WP5874-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: ERK 1
Reactivity: Human,Mouse,Rat
Application: IHC,IF
MW(Calculated): --
MW(Observed): 44kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-300;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Recombinant Protein of ERK1
Sequence: --
Specificity: The antibody detects endogenous ERK1 protein
Gene Name: MAPK3 ERK1 PRKM3
Protein Name: Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Other Name: MAPK3;ERK1;PRKM3;Mitogen-activated protein kinase 3;MAP kinase 3;MAPK 3;ERT2;Extracellular signal-regulated kinase 1;ERK-1;Insulin-stimulated MAP2 kinase;MAP kinase isoform p44;p44-MAPK;Microtubule-associated protein 2 kinase;p
Organism-1: Human
Gene ID-1: 5595
SwissProt-1: P27361
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q63844
Organism-3: Rat
Gene ID-3: --
SwissProt-3: P21708
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus. Membrane, caveola . Cell junction, focal adhesion . Autophosphorylation at Thr-207 promotes nuclear localization (PubMed:19060905). PEA15-binding redirects the biological outcome of MAPK3 kinase-signaling by sequestering MAPK3 into the cytoplasm (By similarity). .