- Target
- ACTN4
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 100kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human ACTN4
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of ACTN4 at Human, Mouse,Rat
- Gene Name
- ACTN4
- Protein Name
- Alpha-actinin-4 (F-actin cross-linking protein) (Non-muscle alpha-actinin 4)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 81
- SwissProt-1
- O43707
- Organism-2
- Mouse
- Gene ID-2
- 60595
- SwissProt-2
- P57780
- Organism-3
- Rat
- Gene ID-3
- 63836
- SwissProt-3
- Q9QXQ0
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Cytoplasm . Cell junction . Cytoplasm, cytoskeleton, stress fiber . Cytoplasm, perinuclear region . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines (breast cancer cell line MCF-7, oral floor cancer IMC-2, and bladder cancer KU-7). .