U-Blot® RNF8 rabbit pAb

Name: U-Blot® RNF8 rabbit pAb
SKU: WP6068
Availability: InStock

$268.00

Size:50μL

SKU: WP6068-50

Catalog No.: WP6068

Specification: 50μL/100μL

Stock: In stock

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U-Blot® RNF8 rabbit pAb

Product Overview

Catalog No.: WP6068
SKU: WP6068-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RNF8
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 53kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human RNF8
Sequence: --
Specificity: This antibody detects endogenous levels of RNF8 at Human, Mouse,Rat
Gene Name: RNF8 KIAA0646
Protein Name: E3 ubiquitin-protein ligase RNF8 (hRNF8) (RING finger protein 8)
Other Name: --
Organism-1: Human
Gene ID-1: 9025
SwissProt-1: O76064
Organism-2: Mouse
Gene ID-2: 58230
SwissProt-2: Q8VC56
Organism-3: Rat
Gene ID-3: 361815
SwissProt-3: Q4KLN8
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Midbody . Chromosome, telomere . Recruited at uncapped telomeres (By similarity). Following DNA damage, such as double-strand breaks, recruited to the sites of damage (PubMed:18001824, PubMed:18077395, PubMed:22266820, PubMed:23233665). During prophase, concomitant with nuclear envelope breakdown, localizes throughout the cell, with a dotted pattern. In telophase, again in the nucleus and also with a discrete dotted pattern in the cytoplasm. In late telophase and during cytokinesis, localizes in the midbody of the tubulin bridge joining the daughter cells. Does not seem to be associated with condensed chromosomes at any time during the cell cycle. During spermatogenesis, sequestered in the cytoplasm by PIWIL1: RNF8 is released following ubiquitination and degradation of PIWIL1. .