- Target
- ZFP36
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 36kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human ZFP36
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of ZFP36 at Human, Mouse,Rat
- Gene Name
- ZFP36 G0S24 RNF162A TIS11A TTP
- Protein Name
- Tristetraprolin (TTP) (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Protein TIS11A) (TIS11) (Zinc finger protein 36 homolog) (Zfp-36)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 7538
- SwissProt-1
- P26651
- Organism-2
- Mouse
- Gene ID-2
- 22695
- SwissProt-2
- P22893
- Organism-3
- Rat
- Gene ID-3
- 79426
- SwissProt-3
- P47973
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Cytoplasm . Cytoplasmic granule . Cytoplasm, P-body . Shuttles between nucleus and cytoplasm in a CRM1-dependent manner (By similarity). Localized predominantly in the cytoplasm in a p38 MAPK- and YWHAB-dependent manner (By similarity). Colocalizes with SH3KBP1 and MAP3K4 in the cytoplasm (PubMed:20221403). Component of cytoplasmic stress granules (SGs) (By similarity). Localizes to cytoplasmic stress granules upon energy starvation (PubMed:15014438). Localizes in processing bodies (PBs) (PubMed:17369404). Excluded from stress granules in a phosphorylation MAPKAPK2-dependent manner (By similarity). Shuttles in and out of both cytoplasmic P-body and SGs (By similarity). .; Nucleus . Cytoplasm . (Microbial infection) Colocalizes with HTLV-1 TAX in the nucleus and the cytoplasm in a region surrounding the nucleus. .