- Target
- DHX36
- Reactivity
- Human,Mouse
- Application
- WB
- MW(Calculated)
- 111kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human DHX36
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of DHX36 at Human, Mouse
- Gene Name
- DHX36 DDX36 KIAA1488 MLEL1 RHAU
- Protein Name
- Probable ATP-dependent RNA helicase DHX36 (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 170506
- SwissProt-1
- Q9H2U1
- Organism-2
- Mouse
- Gene ID-2
- 72162
- SwissProt-2
- Q8VHK9
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Cytoplasm . Cytoplasm, cytosol . Cytoplasm, Stress granule . Nucleus speckle . Chromosome, telomere . Mitochondrion . Perikaryon . Cell projection, dendrite . Cell projection, axon . Predominantly localized in the nucleus (PubMed:18279852). Colocalizes with SRSF2 in nuclear speckles (PubMed:18279852). Colocalizes with DDX5 in nucleolar caps upon transcription inhibition (PubMed:18279852). Accumulates and colocalized with TIA1 in cytoplasmic stress granules (SGs) in an arsenite-, heat shock- and RNA-binding-dependent manner (PubMed:18854321). Shuttles into and out of SGs in an ATPase-dependent manner (PubMed:18854321). Colocalizes in the cytosol with the multi-helicase-TICAM1 complex that translocates to the mitochondria upon poly(I:C) RNA ligand stimulation (By similarity). .; [Isoform 1]: Nucleus . Cytoplasm . Preferentially localized in the nucleus (PubMed:14731398). Excluded from nucleoli (PubMed:14731398). .; [Isoform 2]: Nucleus . Cytoplasm . Preferentially localized in the cytoplasm (PubMed:14731398). Excluded from nucleoli (PubMed:14731398). .