U-Blot® CRACR2A rabbit pAb

Name: U-Blot® CRACR2A rabbit pAb
SKU: WP6522
Availability: InStock

$268.00

Size:50μL

SKU: WP6522-50

Catalog No.: WP6522

Specification: 50μL/100μL

Stock: In stock

U-Blot® CRACR2A rabbit pAb Learn more

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U-Blot® CRACR2A rabbit pAb

Product Overview

Catalog No.: WP6522
SKU: WP6522-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CRACR2A
Reactivity: Human,Mouse
Application: WB
MW(Calculated): 80kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human CRACR2A
Sequence: --
Specificity: This antibody detects endogenous levels of CRACR2A at Human, Mouse
Gene Name: EFCAB4B CRACR2A
Protein Name: EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A)
Other Name: --
Organism-1: Human
Gene ID-1: 84766
SwissProt-1: Q9BSW2
Organism-2: Mouse
Gene ID-2: 381812
SwissProt-2: Q3UP38
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Cytoplasm .; [Isoform 2]: Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center . Cell membrane . Golgi apparatus membrane . Golgi apparatus, trans-Golgi network membrane . Vesicle . T-cell activation-induced elevation of intracellular of Ca(2+) stimulates its transport toward the microtubule organizing center (MTOC) (PubMed:30814157). Histamine stimulation induces a trafficking to the MTOC in a GTP-binding-dependent but Ca(2+)-binding-independent manner (PubMed:31092558). Localizes to Golgi membrane in resting T-cells and upon its interaction with VAV1, is translocated from the Golgi membrane to the immunological synapse via subsynaptic vesicles (PubMed:27016526). Its localization in the Golgi membrane requires isoprenylation and GTP-binding (PubMed:27016526). .