U-Blot® SMC5 rabbit pAb

Name: U-Blot® SMC5 rabbit pAb
SKU: WP6708
Availability: InStock

$268.00

Size:50μL

SKU: WP6708-50

Catalog No.: WP6708

Specification: 50μL/100μL

Stock: In stock

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U-Blot® SMC5 rabbit pAb

Product Overview

Catalog No.: WP6708
SKU: WP6708-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SMC5
Reactivity: Human,Mouse
Application: WB
MW(Calculated): 121kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human SMC5
Sequence: --
Specificity: This antibody detects endogenous levels of SMC5 at Human, Mouse
Gene Name: SMC5 KIAA0594 SMC5L1
Protein Name: Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Other Name: --
Organism-1: Human
Gene ID-1: 23137
SwissProt-1: Q8IY18
Organism-2: Mouse
Gene ID-2: 226026
SwissProt-2: Q8CG46
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome . Nucleus, PML body . Chromosome, telomere . Associates with chromatin (PubMed:25931565). Colocalizes with SMC6 on the X-Y chromosome pair within the sex vesicle during late pachytene/diplotene (By similarity). Localizes to PML nuclear bodies in ALT cell lines (PubMed:17589526). Accumulates with RAD18 and the SLF1-SLF2 complex at replication-coupled DNA interstrand repair and DNA double-strand breaks (DSBs) sites on chromatin in a ubiquitin-dependent manner (PubMed:25931565). .