U-Blot® WDFY3 rabbit pAb

Name: U-Blot® WDFY3 rabbit pAb
SKU: WP6770
Availability: InStock

$268.00

Size:50μL

SKU: WP6770-50

Catalog No.: WP6770

Specification: 50μL/100μL

Stock: In stock

U-Blot® WDFY3 rabbit pAb Learn more

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U-Blot® WDFY3 rabbit pAb

Product Overview

Catalog No.: WP6770
SKU: WP6770-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: WDFY3
Reactivity: Human,Mouse
Application: WB
MW(Calculated): 388kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human WDFY3
Sequence: --
Specificity: This antibody detects endogenous levels of WDFY3 at Human, Mouse
Gene Name: WDFY3 KIAA0993
Protein Name: WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Other Name: --
Organism-1: Human
Gene ID-1: 23001
SwissProt-1: Q8IZQ1
Organism-2: Mouse
Gene ID-2: 72145
SwissProt-2: Q6VNB8
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus membrane . Cytoplasm, cytosol . Nucleus, PML body . Membrane; Peripheral membrane protein ; Cytoplasmic side . Perikaryon . Cell projection, axon . Relocalization from the nucleus to the cytosol is stimulated by cellular stress, such as starvation or proteasomal inhibition. In the cytosol of starved cells, colocalizes with autophagic structures (PubMed:15292400, PubMed:20168092, PubMed:20971078, PubMed:20417604). This redistribution is dependent on p62/SQSTM1 (PubMed:20168092). When nuclear export is blocked by treatment with leptomycin B, accumulates in nuclear bodies, that completely or partially colocalize with promyelocytic leukemia (PML) bodies (PubMed:20168092). Localizes throughout neurons, including within axons. In neurons, enriched in the light membrane fraction along with the synaptosomal membrane protein synaptophysin and the membrane-bound form of LC3/MAP1LC3A/MAP1LC3B, called LC3-II, a classic marker for autophagic vesicles (By similarity). .