U-Blot® Myopodin rabbit pAb

Name: U-Blot® Myopodin rabbit pAb
SKU: WP7120
Availability: InStock

$268.00

Size:50μL

SKU: WP7120-50

Catalog No.: WP7120

Specification: 50μL/100μL

Stock: In stock

U-Blot® Myopodin rabbit pAb Learn more

Product details Specifications Q & A Education

U-Blot® Myopodin rabbit pAb

Product Overview

Catalog No.: WP7120
SKU: WP7120-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SYNPO2
Reactivity: Human
Application: WB
MW(Calculated): 120kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human Myopodin
Sequence: --
Specificity: This antibody detects endogenous levels of Myopodin at Human
Gene Name: SYNPO2
Protein Name: Synaptopodin-2 (Genethonin-2) (Myopodin)
Other Name: --
Organism-1: Human
Gene ID-1: 171024
SwissProt-1: Q9UMS6
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q91YE8
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Cell junction, focal adhesion . Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. In undifferentiated myoblasts strongly expressed in the nucleus, after induction of myotube differentiation is located to both nucleus and cytoplasm along acting filaments, and in differentiated myotubes is located at the Z lines. Upon stress redistributes from cytoplasm of myoblasts and myotubes to the nucleus. Nuclear import is KPNA2-dependent and promoted by phosphorylation by PKA and/or CaMK2, and inhibition of calcineurin. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern, partly overlapping with filamentous actin (PubMed:18371299). .; [Isoform 1]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with contiguous staining. .; [Isoform 2]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with punctuate staining. .; [Isoform 3]: Cytoplasm, cytoskeleton . Localizes to induced irregular actin bundles with contiguous and punctuated staining. .; [Isoform 4]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with punctuate staining. .; [Isoform 5]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with contiguous staining. .