U-Blot® TREX1 rabbit pAb

Name: U-Blot® TREX1 rabbit pAb
SKU: WP7621
Availability: InStock

$268.00

Size:50μL

SKU: WP7621-50

Catalog No.: WP7621

Specification: 50μL/100μL

Stock: In stock

U-Blot® TREX1 rabbit pAb Learn more

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U-Blot® TREX1 rabbit pAb

Product Overview

Catalog No.: WP7621
SKU: WP7621-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: TREX1
Reactivity: Human,Mouse
Application: WB
MW(Calculated): 35kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human TREX1
Sequence: --
Specificity: This antibody detects endogenous levels of TREX1 at Human, Mouse
Gene Name: TREX1
Protein Name: Three prime repair exonuclease 1 (3'-5' exonuclease TREX1) (DNase III)
Other Name: --
Organism-1: Human
Gene ID-1: 11277
SwissProt-1: Q9NSU2
Organism-2: Mouse
Gene ID-2: 22040
SwissProt-2: Q91XB0
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm, cytosol . Endoplasmic reticulum membrane ; Peripheral membrane protein . Retained in the cytoplasm through the C-terminal region (By similarity). Localization to the endoplasmic reticulum membrane is required to direct TREX1 to ruptured micronuclei (PubMed:33476576). In response to DNA damage, translocates to the nucleus where it is specifically recruited to replication foci (PubMed:16818237). Translocation to the nucleus also occurs during GZMA-mediated cell death (PubMed:16818237). .