- Target
- OBSCN
- Reactivity
- Human
- Application
- WB
- MW(Calculated)
- 876kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human OBSCN
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of OBSCN at Human
- Gene Name
- OBSCN KIAA1556 KIAA1639
- Protein Name
- Obscurin (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 84033
- SwissProt-1
- Q5VST9
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- A2AAJ9
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- [Isoform 3]: Cytoplasm, myofibril, sarcomere, M line . Cytoplasm, myofibril, sarcomere, Z line . In differentiating skeletal muscle cells, isoform 3 primarily localizes to the sarcomeric M-line and less frequently to the Z-disk (PubMed:12527750). Isoform 3 colocalizes with ANK1 isoform Mu17/ank1.5 at the M-line in differentiated skeletal muscle cells (PubMed:12527750).; Cytoplasm, myofibril, sarcomere, M line . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane, sarcolemma . Nucleus . Colocalizes with CDH2 and ATP1B1 to the sarcolemma and to intercalating disks in cardiac muscles. Colocalizes with ATP1B1 to M line and Z line in cardiac muscles. .