U-Blot® Polycystin 1 rabbit pAb

Name: U-Blot® Polycystin 1 rabbit pAb
SKU: WP7749
Availability: InStock

$268.00

Size:50μL

SKU: WP7749-50

Catalog No.: WP7749

Specification: 50μL/100μL

Stock: In stock

U-Blot® Polycystin 1 rabbit pAb Learn more

Product details Specifications Q & A Education

U-Blot® Polycystin 1 rabbit pAb

Product Overview

Catalog No.: WP7749
SKU: WP7749-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PKD1
Reactivity: Human,Mouse
Application: WB
MW(Calculated): 473kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 4100-4150
Sequence: --
Specificity: This antibody detects endogenous levels of Polycystin 1 at Human, Mouse
Gene Name: PKD1
Protein Name: Polycystin-1 (Autosomal dominant polycystic kidney disease 1 protein)
Other Name: --
Organism-1: Human
Gene ID-1: 5310
SwissProt-1: P98161
Organism-2: Mouse
Gene ID-2: 18763
SwissProt-2: O08852
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Cell projection, cilium . Endoplasmic reticulum . Golgi apparatus . PKD1 localization to the plasma and ciliary membranes requires PKD2, is independent of PKD2 channel activity, and involves stimulation of PKD1 autoproteolytic cleavage at the GPS domain. PKD1:PKD2 interaction is required to reach the Golgi apparatus from endoplasmic reticulum and then traffic to the cilia (By similarity). Ciliary localization of PKD1 requires BBS1 and ARL6/BBS3 (By similarity). Cell surface localization requires GANAB (PubMed:27259053). .