- Target
- LIMD1
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 74kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human LIMD1
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of LIMD1 at Human, Mouse,Rat
- Gene Name
- LIMD1
- Protein Name
- LIM domain-containing protein 1
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 8994
- SwissProt-1
- Q9UGP4
- Organism-2
- Mouse
- Gene ID-2
- 29806
- SwissProt-2
- Q9QXD8
- Organism-3
- Rat
- Gene ID-3
- 316101
- SwissProt-3
- B5DEH0
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm. Nucleus. Cytoplasm, P-body. Cell junction, adherens junction. Cell junction, focal adhesion. Shuttles between cytoplasm and nucleus but is localized predominantly to the cytoplasm. Found in the nucleus but not nucleoli. Colocalizes with VCL in the focal adhesions. Down-regulation and/or elimination of its expression from the nucleus of neoplastic cells correlates strongly with poor patient prognosis and aggressive forms of breast carcinoma. Conversely, strong nuclear localization correlates with low-tumor grade and better patient prognosis.