- Target
- SIRT7
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 44kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human SIRT7
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of SIRT7 at Human, Mouse,Rat
- Gene Name
- SIRT7 SIR2L7
- Protein Name
- NAD-dependent protein deacetylase sirtuin-7 (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 51547
- SwissProt-1
- Q9NRC8
- Organism-2
- Mouse
- Gene ID-2
- 209011
- SwissProt-2
- Q8BKJ9
- Organism-3
- Rat
- Gene ID-3
- 303745
- SwissProt-3
- B2RZ55
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus, nucleolus . Nucleus, nucleoplasm . Chromosome . Cytoplasm . Mainly localizes in the nucleolus and nucleoplasm (PubMed:24207024, PubMed:28886238, PubMed:28790157, PubMed:31075303). Associated with rDNA promoter and transcribed region (PubMed:16079181, PubMed:19174463). Associated with nucleolar organizer regions during mitosis (PubMed:16079181, PubMed:19174463). In response to stress, released from nucleolus to nucleoplasm (PubMed:24207024). Associated with chromatin (PubMed:22722849). In response to DNA damage, recruited to DNA double-strand breaks (DSBs) sites (PubMed:27436229) (Probable). Located close to the nuclear membrane when in the cytoplasm (PubMed:11953824). .