- Target
- LEMD2
- Reactivity
- Human,Mouse
- Application
- WB
- MW(Calculated)
- 55kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human LEMD2
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of LEMD2 at Human, Mouse
- Gene Name
- LEMD2
- Protein Name
- LEM domain-containing protein 2 (hLEM2)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 221496
- SwissProt-1
- Q8NC56
- Organism-2
- Mouse
- Gene ID-2
- 224640
- SwissProt-2
- Q6DVA0
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus inner membrane ; Multi-pass membrane protein . Nucleus envelope . Cytoplasm, cytoskeleton, spindle . Lamina-associated protein residing in the inner nuclear membrane (INM) of the nuclear envelope (NE) (PubMed:16339967). The localization to the INM is dependent on LMNA (PubMed:16339967). Evenly distributed around the NE during interphase (PubMed:16339967). During metaphase, found in a reticular network (PubMed:28242692). Recruited to the reforming NE on chromatin disks in early anaphase (PubMed:28242692). In late anaphase, concentrates at the NE core proximal to spindle microtubules, and then broadening to a distributed nuclear rim pattern (PubMed:28242692, PubMed:32494070). .