U-Blot® Shootin 1 rabbit pAb

Name: U-Blot® Shootin 1 rabbit pAb
SKU: WP8524
Availability: InStock

$268.00

Size:50μL

SKU: WP8524-50

Catalog No.: WP8524

Specification: 50μL/100μL

Stock: In stock

U-Blot® Shootin 1 rabbit pAb Learn more

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U-Blot® Shootin 1 rabbit pAb

Product Overview

Catalog No.: WP8524
SKU: WP8524-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SHTN1
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 69kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human Shootin 1
Sequence: --
Specificity: This antibody detects endogenous levels of Shootin 1 at Human, Mouse,Rat
Gene Name: KIAA1598
Protein Name: Shootin-1
Other Name: --
Organism-1: Human
Gene ID-1: 57698
SwissProt-1: A0MZ66
Organism-2: Mouse
Gene ID-2: 71653
SwissProt-2: Q8K2Q9
Organism-3: Rat
Gene ID-3: 292139
SwissProt-3: A0MZ67
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Perikaryon . Cell projection, axon . Cell projection, growth cone . Cytoplasm, cytoskeleton . Cell projection, filopodium . Cell projection, lamellipodium . Localizes in multiple growth cones at neurite tips before the neuronal symmetry-breaking step. Accumulates in growth cones of a single nascent axon in a neurite length-dependent manner during the neuronal symmetry-breaking step; when absent from the nascent axon's siblings, probably due to competitive transport, prevents the formation of surplus axons. Transported anterogradely from the soma to the axon growth cone in an actin and myosin-dependent manner and passively diffuses back to the cell bodies. Colocalized with L1CAM in close apposition with actin filaments in filopodia and lamellipodia of axonal growth cones in hippocampal neurons. Exhibits retrograde movements in filopodia and lamellopodia of axonal growth cones. Colocalized with KIF20B along microtubules to the tip of the growing cone in primary hippocampal neurons. Recruited to the growth cone of developing axon in a KIF20B- and microtubule-dependent manner. .