- Target
- ABRAXAS2
- Reactivity
- Human,Mouse
- Application
- WB
- MW(Calculated)
- 46kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human FAM175B
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of FAM175B at Human, Mouse
- Gene Name
- FAM175B ABRO1 KIAA0157
- Protein Name
- BRISC complex subunit Abro1 (Abraxas brother protein 1) (Protein FAM175B)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 23172
- SwissProt-1
- Q15018
- Organism-2
- Mouse
- Gene ID-2
- 109359
- SwissProt-2
- Q3TCJ1
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton . A minor proportion is detected in the nucleus (PubMed:21282113, PubMed:22974638). Translocates into the nucleus in response to DNA damage (PubMed:25283148). Directly binds to microtubules and is detected at the minus end of K-fibers (PubMed:26195665). Co-localizes with NUMA1 at mitotic spindle poles (PubMed:26195665). .