- Target
- NIN
- Reactivity
- Human,Mouse
- Application
- WB
- MW(Calculated)
- 230kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human Ninein
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Ninein at Human, Mouse
- Gene Name
- NIN KIAA1565
- Protein Name
- Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 51199
- SwissProt-1
- Q8N4C6
- Organism-2
- Mouse
- Gene ID-2
- 18080
- SwissProt-2
- Q61043
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Component of the core centrosome. Arranged in a tubular conformation with an open and a closed end within the centrosome. In the mother centrosome, it localizes at both ends of the centrosome tube, including the site of centrosome duplication, while in the daughter centrosome it is present only at the closed end. Requires PCM1 for centrosome localization. Localizes to the subdistal appendage region of the centriole in a DCTN1-dependent manner. .; [Isoform 6]: Cytoplasm . Seems to have a dominant-negative effect on localization of other isoforms, promoting their dissociation from the centrosome. .