U-Blot® Erbin (phospho Tyr1104) Polyclonal Antibody

Name: U-Blot® Erbin (phospho Tyr1104) Polyclonal Antibody
SKU: WP9132
Availability: InStock

$288.00

Size:50μL

SKU: WP9132-50

Catalog No.: WP9132

Specification: 50μL/100μL

Stock: In stock

U-Blot® Erbin (phospho Tyr1104) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Product Overview

Catalog No.: WP9132
SKU: WP9132-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Erbin
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 172kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Erbin (phospho Tyr1104)
Sequence: --
Specificity: Phospho-Erbin (Y1104) Polyclonal Antibody detects endogenous levels of Erbin protein only when phosphorylated at Y1104.
Gene Name: ERBB2IP
Protein Name: Protein LAP2
Other Name: ERBB2IP;ERBIN;KIAA1225;LAP2;Protein LAP2;Densin-180-like protein;Erbb2-interacting protein;Erbin
Organism-1: Human
Gene ID-1: 55914
SwissProt-1: Q96RT1
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q80TH2
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell junction, hemidesmosome . Nucleus membrane . Basolateral cell membrane . Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity). .