U-Blot® G3BP1 (phospho Ser232) Polyclonal Antibody

Name: U-Blot® G3BP1 (phospho Ser232) Polyclonal Antibody
SKU: WP9150
Availability: InStock

$288.00

Size:50μL

SKU: WP9150-50

Catalog No.: WP9150

Specification: 50μL/100μL

Stock: In stock

U-Blot® G3BP1 (phospho Ser232) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9150
SKU: WP9150-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: G3BP1
Reactivity: Human,Mouse
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 60kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human G3BP-1 around the phosphorylation site of Ser232. AA range:216-248
Sequence: --
Specificity: Phospho-G3BP1 (S232) Polyclonal Antibody detects endogenous levels of G3BP1 protein only when phosphorylated at S232.
Gene Name: G3BP1
Protein Name: Ras GTPase-activating protein-binding protein 1
Other Name: G3BP1;G3BP;Ras GTPase-activating protein-binding protein 1;G3BP-1;ATP-dependent DNA helicase VIII;hDH VIII;GAP SH3 domain-binding protein 1
Organism-1: Human
Gene ID-1: 10146
SwissProt-1: Q13283
Organism-2: Mouse
Gene ID-2: 27041
SwissProt-2: P97855
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol . Perikaryon . Cytoplasm, Stress granule . Nucleus . Cytoplasmic in proliferating cells (PubMed:11604510). Cytosolic and partially nuclear in resting cells (PubMed:11604510). Recruited to stress granules in response to arsenite treatment (PubMed:12642610, PubMed:20180778). The unphosphorylated form is recruited to stress granules (PubMed:12642610). HRAS signaling contributes to this process by regulating G3BP dephosphorylation (PubMed:12642610). .