U-Blot® GSK3β (phospho Ser9) Polyclonal Antibody

Name: U-Blot® GSK3β (phospho Ser9) Polyclonal Antibody
SKU: WP9157
Availability: InStock

$288.00

Size:50μL

SKU: WP9157-50

Catalog No.: WP9157

Specification: 50μL/100μL

Stock: In stock

U-Blot® GSK3β (phospho Ser9) Polyclonal Antibody Learn more

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Background：The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],

Product Overview

Catalog No.: WP9157
SKU: WP9157-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GSK3β
Reactivity: Human,Mouse,Rat,Drosophila
Application: IF,WB,IHC,IP,ELISA
MW(Calculated): --
MW(Observed): 48kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:5000;Not yet tested in other applications;
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GSK3 beta around the phosphorylation site of Ser9. AA range:1-50
Sequence: --
Specificity: Phospho-GSK3β (S9) Polyclonal Antibody detects endogenous levels of GSK3β protein only when phosphorylated at S9.
Gene Name: GSK3B
Protein Name: Glycogen synthase kinase-3 beta
Other Name: GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B
Organism-1: Human
Gene ID-1: 2932
SwissProt-1: P49841
Organism-2: Mouse
Gene ID-2: 56637
SwissProt-2: Q9WV60
Organism-3: Rat
Gene ID-3: 84027
SwissProt-3: P18266
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .