U-Blot® RUNX1 (phospho Ser249) Polyclonal Antibody

Name: U-Blot® RUNX1 (phospho Ser249) Polyclonal Antibody
SKU: WP9326
Availability: InStock

$288.00

Size:50μL

SKU: WP9326-50

Catalog No.: WP9326

Specification: 50μL/100μL

Stock: In stock

U-Blot® RUNX1 (phospho Ser249) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9326
SKU: WP9326-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RUNX1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 49kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human AML1 around the phosphorylation site of Ser276. AA range:242-291
Sequence: --
Specificity: Phospho-RUNX1 (S249) Polyclonal Antibody detects endogenous levels of RUNX1 protein only when phosphorylated at S249.
Gene Name: RUNX1
Protein Name: Runt-related transcription factor 1
Other Name: RUNX1;AML1;CBFA2;Runt-related transcription factor 1;Acute myeloid leukemia 1 protein;Core-binding factor subunit alpha-2;CBF-alpha-2;Oncogene AML-1;Polyomavirus enhancer-binding protein 2 alpha B subunit;PEA2-alpha B;PEBP2-alpha
Organism-1: Human
Gene ID-1: 861
SwissProt-1: Q01196
Organism-2: Mouse
Gene ID-2: 12394
SwissProt-2: Q03347
Organism-3: Rat
Gene ID-3: 50662
SwissProt-3: Q63046
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus.