U-Blot® Pim-1 (phospho Tyr309) Polyclonal Antibody

Name: U-Blot® Pim-1 (phospho Tyr309) Polyclonal Antibody
SKU: WP9364
Availability: InStock

$288.00

Size:50μL

SKU: WP9364-50

Catalog No.: WP9364

Specification: 50μL/100μL

Stock: In stock

U-Blot® Pim-1 (phospho Tyr309) Polyclonal Antibody Learn more

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Background：The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011],

Product Overview

Catalog No.: WP9364
SKU: WP9364-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Pim-1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 45kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Pim-1 around the phosphorylation site of Tyr309. AA range:281-330
Sequence: --
Specificity: Phospho-Pim-1 (Y309) Polyclonal Antibody detects endogenous levels of Pim-1 protein only when phosphorylated at Y309.
Gene Name: PIM1
Protein Name: Serine/threonine-protein kinase pim-1
Other Name: PIM1;Serine/threonine-protein kinase pim-1
Organism-1: Human
Gene ID-1: 5292
SwissProt-1: P11309
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P06803
Organism-3: Rat
Gene ID-3: 24649
SwissProt-3: P26794
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 2]: Cell membrane.