U-Blot® PKD2 (phospho Ser876) Polyclonal Antibody

Name: U-Blot® PKD2 (phospho Ser876) Polyclonal Antibody
SKU: WP9374
Availability: InStock

$288.00

Size:50μL

SKU: WP9374-50

Catalog No.: WP9374

Specification: 50μL/100μL

Stock: In stock

U-Blot® PKD2 (phospho Ser876) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9374
SKU: WP9374-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PKD2
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 96kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human PKD2 around the phosphorylation site of Ser876. AA range:829-878
Sequence: --
Specificity: Phospho-PKD2 (S876) Polyclonal Antibody detects endogenous levels of PKD2 protein only when phosphorylated at S876.
Gene Name: PRKD2
Protein Name: Serine/threonine-protein kinase D2
Other Name: PRKD2;PKD2;HSPC187;Serine/threonine-protein kinase D2;nPKC-D2
Organism-1: Human
Gene ID-1: 25865
SwissProt-1: Q9BZL6
Organism-2: Mouse
Gene ID-2: 101540
SwissProt-2: Q8BZ03
Organism-3: Rat
Gene ID-3: 292658
SwissProt-3: Q5XIS9
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell membrane . Nucleus . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation. Accumulates in the nucleus upon CK1-mediated phosphorylation after activation of G-protein-coupled receptors. Nuclear accumulation is regulated by blocking nuclear export of active PRKD2 rather than by increasing import. .