U-Blot® IL-10Rα (phospho Tyr496) Polyclonal Antibody

Name: U-Blot® IL-10Rα (phospho Tyr496) Polyclonal Antibody
SKU: WP9401
Availability: InStock

$288.00

Size:50μL

SKU: WP9401-50

Catalog No.: WP9401

Specification: 50μL/100μL

Stock: In stock

U-Blot® IL-10Rα (phospho Tyr496) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009],

Product Overview

Catalog No.: WP9401
SKU: WP9401-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IL-10Rα
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 63kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human IL-10R alpha around the phosphorylation site of Tyr496. AA range:462-511
Sequence: --
Specificity: Phospho-IL-10Rα (Y496) Polyclonal Antibody detects endogenous levels of IL-10Rα protein only when phosphorylated at Y496.
Gene Name: IL10RA
Protein Name: Interleukin-10 receptor subunit alpha
Other Name: IL10RA;IL10R;Interleukin-10 receptor subunit alpha;IL-10 receptor subunit alpha;IL-10R subunit alpha;IL-10RA;CDw210a;Interleukin-10 receptor subunit 1;IL-10R subunit 1;IL-10R1;CD antigen CD210
Organism-1: Human
Gene ID-1: 3587
SwissProt-1: Q13651
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q61727
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Single-pass type I membrane protein. Cytoplasm .