U-Blot® eNOS (phospho Ser615) Polyclonal Antibody

Name: U-Blot® eNOS (phospho Ser615) Polyclonal Antibody
SKU: WP9414
Availability: InStock

$288.00

Size:50μL

SKU: WP9414-50

Catalog No.: WP9414

Specification: 50μL/100μL

Stock: In stock

U-Blot® eNOS (phospho Ser615) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Product Overview

Catalog No.: WP9414
SKU: WP9414-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: NOS3
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 130-140kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human eNOS around the phosphorylation site of Ser615. AA range:581-630
Sequence: --
Specificity: Phospho-NOS3 (S615) Polyclonal Antibody detects endogenous levels of NOS3 protein only when phosphorylated at S615.
Gene Name: NOS3
Protein Name: Nitric oxide synthase endothelial
Other Name: NOS3;Nitric oxide synthase;endothelial;Constitutive NOS;cNOS;EC-NOS;Endothelial NOS;eNOS;NOS type III;NOSIII
Organism-1: Human
Gene ID-1: 4846
SwissProt-1: P29474
Organism-2: Mouse
Gene ID-2: 18127
SwissProt-2: P70313
Organism-3: Rat
Gene ID-3: 24600
SwissProt-3: Q62600
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.