U-Blot® Casein Kinase Iα (phospho Thr321) Polyclonal Antibody

Name: U-Blot® Casein Kinase Iα (phospho Thr321) Polyclonal Antibody
SKU: WP9425
Availability: InStock

$288.00

Size:50μL

SKU: WP9425-50

Catalog No.: WP9425

Specification: 50μL/100μL

Stock: In stock

U-Blot® Casein Kinase Iα (phospho Thr321) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex.,

Product Overview

Catalog No.: WP9425
SKU: WP9425-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Casein Kinase Iα
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 35kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Casein Kinase I alpha around the phosphorylation site of Tyr321. AA range:287-336
Sequence: --
Specificity: Phospho-Casein Kinase Iα (Y321) Polyclonal Antibody detects endogenous levels of Casein Kinase Iα protein only when phosphorylated at Y321.
Gene Name: CSNK1A1
Protein Name: Casein kinase I isoform alpha
Other Name: CSNK1A1;Casein kinase I isoform alpha;CKI-alpha;CK1
Organism-1: Human
Gene ID-1: 1452
SwissProt-1: P48729
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q8BK63
Organism-3: Rat
Gene ID-3: 113927
SwissProt-3: P97633
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome, centromere, kinetochore . Nucleus speckle . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, spindle . Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688). .