U-Blot® Ezrin (phospho Tyr478) Polyclonal Antibody

Name: U-Blot® Ezrin (phospho Tyr478) Polyclonal Antibody
SKU: WP9443
Availability: InStock

$288.00

Size:50μL

SKU: WP9443-50

Catalog No.: WP9443

Specification: 50μL/100μL

Stock: In stock

U-Blot® Ezrin (phospho Tyr478) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9443
SKU: WP9443-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Ezrin
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 70kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr478. AA range:446-495
Sequence: --
Specificity: Phospho-Ezrin (Y478) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y478.
Gene Name: EZR
Protein Name: Ezrin
Other Name: EZR;VIL2;Ezrin;Cytovillin;Villin-2;p81
Organism-1: Human
Gene ID-1: 7430
SwissProt-1: P15311
Organism-2: Mouse
Gene ID-2: 22350
SwissProt-2: P26040
Organism-3: Rat
Gene ID-3: 54319
SwissProt-3: P31977
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell projection, microvillus . Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side). .