U-Blot® Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody

Name: U-Blot® Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody
SKU: WP9454
Availability: InStock

$288.00

Size:50μL

SKU: WP9454-50

Catalog No.: WP9454

Specification: 50μL/100μL

Stock: In stock

U-Blot® Intestinal Cell Kinase (phospho Tyr159) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9454
SKU: WP9454-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Intestinal Cell Kinase
Reactivity: Human,Mouse,Rat
Application: WB,ELISA,IHC
MW(Calculated): --
MW(Observed): 71kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ICK around the phosphorylation site of Tyr159. AA range:125-174
Sequence: --
Specificity: Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein only when phosphorylated at Y159.
Gene Name: ICK
Protein Name: Serine/threonine-protein kinase ICK
Other Name: ICK;KIAA0936;Serine/threonine-protein kinase ICK;Intestinal cell kinase;hICK;Laryngeal cancer kinase 2;LCK2;MAK-related kinase;MRK
Organism-1: Human
Gene ID-1: 22858
SwissProt-1: Q9UPZ9
Organism-2: Mouse
Gene ID-2: 56542
SwissProt-2: Q9JKV2
Organism-3: Rat
Gene ID-3: 84411
SwissProt-3: Q62726
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm, cytosol . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Also found at the ciliary tip (PubMed:24797473). Nuclear localization has been observed with a GFP-tagged construct in transfected HeLa cells (PubMed:12103360, PubMed:19185282). .; [Isoform 2]: Cytoplasm . Predominant cytoplasmic localization has been observed with a N-terminally GFP-tagged construct. .