U-Blot® AIRE-1 (phospho Ser156) Polyclonal Antibody

Name: U-Blot® AIRE-1 (phospho Ser156) Polyclonal Antibody
SKU: WP9491
Availability: InStock

$288.00

Size:50μL

SKU: WP9491-50

Catalog No.: WP9491

Specification: 50μL/100μL

Stock: In stock

U-Blot® AIRE-1 (phospho Ser156) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012],

Product Overview

Catalog No.: WP9491
SKU: WP9491-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: AIRE-1
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 50kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human AIRE around the phosphorylation site of Ser156. AA range:126-175
Sequence: --
Specificity: Phospho-AIRE-1 (S156) Polyclonal Antibody detects endogenous levels of AIRE-1 protein only when phosphorylated at S156.
Gene Name: AIRE
Protein Name: Autoimmune regulator
Other Name: AIRE;APECED;Autoimmune regulator;Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;APECED protein
Organism-1: Human
Gene ID-1: 326
SwissProt-1: O43918
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9Z0E3
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Predominantly nuclear but also cytoplasmic (PubMed:11274163, PubMed:14974083). Found in nuclear body-like structures (dots) and in a filamentous vimentin-like pattern (PubMed:11274163, PubMed:14974083, PubMed:26084028). Associated with tubular structures (PubMed:11274163, PubMed:14974083). .