U-Blot® Eps15 (phospho Tyr849) Polyclonal Antibody

Name: U-Blot® Eps15 (phospho Tyr849) Polyclonal Antibody
SKU: WP9502
Availability: InStock

$288.00

Size:50μL

SKU: WP9502-50

Catalog No.: WP9502

Specification: 50μL/100μL

Stock: In stock

U-Blot® Eps15 (phospho Tyr849) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009],

Product Overview

Catalog No.: WP9502
SKU: WP9502-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Eps15
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 100kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Eps15 (phospho Tyr849)
Sequence: --
Specificity: Phospho-Eps15 (Y849) Polyclonal Antibody detects endogenous levels of Eps15 protein only when phosphorylated at Y849.
Gene Name: EPS15
Protein Name: Epidermal growth factor receptor substrate 15
Other Name: EPS15;AF1P;Epidermal growth factor receptor substrate 15;Protein Eps15;Protein AF-1p
Organism-1: Human
Gene ID-1: 2060
SwissProt-1: P42566
Organism-2: Mouse
Gene ID-2: 13858
SwissProt-2: P42567
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Recruited to the plasma membrane upon EGFR activation and localizes to coated pits. Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments and in cytoplasmic juxtanuclear structures called aggresomes. .; [Isoform 2]: Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Colocalizes with HGS on bilayered clathrin coats on endosomes.