U-Blot® PAK5/6 (phospho Ser602/S560) Polyclonal Antibody

Name: U-Blot® PAK5/6 (phospho Ser602/S560) Polyclonal Antibody
SKU: WP9508
Availability: InStock

$288.00

Size:50μL

SKU: WP9508-50

Catalog No.: WP9508

Specification: 50μL/100μL

Stock: In stock

U-Blot® PAK5/6 (phospho Ser602/S560) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9508
SKU: WP9508-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PAK5/6
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 75kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human PAK5/6 around the phosphorylation site of Ser602/Ser560. AA range:566-615
Sequence: --
Specificity: Phospho-PAK5/6 (S602/S560) Polyclonal Antibody detects endogenous levels of PAK5/6 protein only when phosphorylated at S602/S560.
Gene Name: PAK6/PAK7
Protein Name: Serine/threonine-protein kinase PAK 6/7
Other Name: PAK7;KIAA1264;PAK5;Serine/threonine-protein kinase PAK 7;p21-activated kinase 5;PAK-5;p21-activated kinase 7;PAK-7;PAK6;PAK5;Serine/threonine-protein kinase PAK 6;PAK-5;p21-activated kinase 6;PAK-6
Organism-1: Human
Gene ID-1: 57144;56924
SwissProt-1: Q9P286;Q9NQU5
Organism-2: Mouse
Gene ID-2: 241656;214230
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Mitochondrion. Cytoplasm. Nucleus. Shuttles between the nucleus and the mitochondria, and mitochondrial localization is essential for the role in cell survival.