U-Blot® HDAC7 (phospho Ser155) Polyclonal Antibody

Name: U-Blot® HDAC7 (phospho Ser155) Polyclonal Antibody
SKU: WP9527
Availability: InStock

$288.00

Size:50μL

SKU: WP9527-50

Catalog No.: WP9527

Specification: 50μL/100μL

Stock: In stock

U-Blot® HDAC7 (phospho Ser155) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9527
SKU: WP9527-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HDAC7
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 103kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC7A around the phosphorylation site of Ser155. AA range:121-170
Sequence: --
Specificity: Phospho-HDAC7 (S155) Polyclonal Antibody detects endogenous levels of HDAC7 protein only when phosphorylated at S155.
Gene Name: HDAC7
Protein Name: Histone deacetylase 7
Other Name: HDAC7;HDAC7A;Histone deacetylase 7;HD7;Histone deacetylase 7A;HD7a
Organism-1: Human
Gene ID-1: 51564
SwissProt-1: Q8WUI4
Organism-2: Mouse
Gene ID-2: 56233
SwissProt-2: Q8C2B3
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q99P96
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus. Cytoplasm. In the nucleus, it associates with distinct subnuclear dot-like structures. Shuttles between the nucleus and the cytoplasm. Treatment with EDN1 results in shuttling from the nucleus to the perinuclear region. The export to cytoplasm depends on the interaction with the 14-3-3 protein YWHAE and is due to its phosphorylation.