U-Blot® NFATc3 (phospho Ser165) Polyclonal Antibody

Name: U-Blot® NFATc3 (phospho Ser165) Polyclonal Antibody
SKU: WP9561
Availability: InStock

$288.00

Size:50μL

SKU: WP9561-50

Catalog No.: WP9561

Specification: 50μL/100μL

Stock: In stock

U-Blot® NFATc3 (phospho Ser165) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010],

Product Overview

Catalog No.: WP9561
SKU: WP9561-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: NFAT4
Reactivity: Human,Mouse
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 115kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human NFAT4 around the phosphorylation site of Ser165. AA range:131-180
Sequence: --
Specificity: Phospho-NFATc3 (S165) Polyclonal Antibody detects endogenous levels of NFATc3 protein only when phosphorylated at S165.
Gene Name: NFATC3
Protein Name: Nuclear factor of activated T-cells cytoplasmic 3
Other Name: NFATC3;NFAT4;Nuclear factor of activated T-cells;cytoplasmic 3;NF-ATc3;NFATc3;NFATx;T-cell transcription factor NFAT4;NF-AT4
Organism-1: Human
Gene ID-1: 4775
SwissProt-1: Q12968
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P97305
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.